HealthieOne's Vitamins and Minerals panel includes 30+ biomarkers spanning everything from 5-Methyltetrahydrofolate and iron studies to a full suite of B vitamins, fat-soluble vitamins, and functional nutrient markers. Instead of vitamin B12 test, HealthieOne measures methylmalonic acid (MMA) and there's a compelling clinical reason why.

The Problem with Testing B12 Directly and MMA is A More Reliable Marker

A conventional serum B12 test tells you how much B12 is circulating in your blood, but it doesn't tell you whether your body is actually using it. As the Cleveland Clinic explains, tests could show normal levels of B12, yet the body may not be able to utilize it, a concept known as bioavailability. Since low B12 causes the body to produce MMA, elevated MMA levels reveal whether B12 is functionally available at the cellular level, even when serum B12 appears adequate. High MMA levels may also allow providers to detect and treat potential health conditions earlier.

Mayo Clinic Laboratories supports this approach, noting that several studies have suggested plasma or urinary methylmalonic acid could be a more reliable marker of vitamin B12 deficiency than direct vitamin B12 determination. Johns Hopkins Healthcare echoes this clinical utility, recognizing MMA as a key diagnostic tool for assessing true B12 status.

What's on the HealthieOne Vitamins and Minerals Panel

HealthieOne's comprehensive panel uses proprietary LC-MS/MS technology to measure over 30 vitamin and mineral biomarkers in a single at-home test, including:

  • B Vitamins (functional): Methylmalonic acid, 5-Methyltetrahydrofolate, Folate, Nicotinamide, Nicotinic acid, Pyridoxal-5'-phosphate, Vitamin B1, B2, B5, B6
  • Fat-Soluble Vitamins: Vitamins A, D, E, K1
  • Minerals & Electrolytes: Calcium, Corrected Calcium, Magnesium, Phosphorus, Iron, Iron % Saturation
  • Iron Metabolism: Ferritin, Transferrin, TIBC, UIBC, Ferritin-to-Albumin Ratio, Ferritin/C-Reactive Protein Ratio
  • Other Functional Markers: Homocysteine, Biotin, Ascorbic acid

By including MMA rather than a simple B12 level, HealthieOne delivers a more clinically actionable picture of your nutritional status, one that reflects what's happening inside your cells, not just in your bloodstream.