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Citrulline

Citrulline

Explanation: Citrulline is an amino acid which can be synthesized by the body. Unlike other amino acids, it isn’t used to build proteins. Instead, citrulline plays a key role in removing ammonia, a waste product, from the body and helps in producing nitric oxide, which improves blood flow and supports heart and muscle health. It’s also found in foods like watermelon.

Test purpose:

  • Detect conditions like citrullinemia: High blood citrulline levels are a hallmark of this condition.
  • Check how well the small intestine is working: Most citrulline in the blood is made by the cells lining the small intestine, so a low level can be a sign that less of that lining is working, for example in untreated celiac disease or after part of the small bowel has been removed.

Other information about this test: Mayo Clinic, MedlinePlus, UCSF Health, ARUP Laboratories

An aspect of Muscle Health.
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